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Artikel dari Berita Kosmo,Selasa,8 Mac,ms13


7 Final Report on the Safety Assessment of Sodium Lauryl Sulfate (SLS) and Ammonium Lauryl Sulfate


Sodium Lauryl Sulfate (SLS) was tested for human skin irritation in concentrations ranging from 0.1 % to 10%. Open patches were less irritating than closed patches, and irritation increased directly with concentration. Similar results were obtained when formulations containing Sodium and Ammonium Lauryl Sulfate were tested. No UV light sensitization occurred from any formulation in this latter study.

Both Sodium and Ammonium Lauryl Sulfate appear to be safe in formulations designed for discontinuous, brief use followed by thorough rinsing from the surface of the skin. In products intended for prolonged contact with skin, concentrations should not exceed 1%.


Final Report of the Amended Safety Assessment of Sodium Laureth Sulfate (SLES) and Related Salts of Sulfated Ethoxylated Alcohols

Sodium Laureth Sulfate  (SLES) is a member of a group of salts of sulfated ethoxylated alcohols, the safety of which was evaluated by the Cosmetic Ingredient Review (CIR) Expert Panel for use in cosmetics. Sodium and ammonium laureth sulfate have not evoked adverse responses in any toxicological testing. Sodium laureth sulfate was demonstrated to be a dermal and ocular irritant but not a sensitizer. The Expert Panel recognized that there are data gaps regarding use and concentration of these ingredients. However, the overall information available on the types of products in which these ingredients are used and at what concentrations indicates a pattern of use. The potential to produce irritation exists with these salts of sulfated ethoxylated alcohols, but in practice they are not regularly seen to be irritating because of the formulations in which they are used. These ingredients should be used only when they can be formulated to be nonirritating.

Valerie C. Robinson, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, James G. Marks, Ronald c. Shank, Thomas J. Slaga, Paul W. Snyder and F. Alan Andersen

International Journal of Toxicology, July 2010; vol. 29, 4 suppl: pp. 151S-161S



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